Advanced semen analysis

Advanced semen analysis : One of the main reasons for infertility in couples - in up to 50% of cases - is male infertility. Male infertility is not necessarily related to male health, as a healthy man can produce poor quality sperm that make conception difficult.

Advanced Semen Analysis in Bangalore

It is therefore very important to perform a semen analysis to determine the fertility potential of the man. A normal semen analysis or seminogram looks at the concentration, motility and morphology of the sperm cells in a semen sample.

While these factors are important in assessing basic sperm quality, there are other components that are far more important in determining the capacity of the sperm to create pregnancy. These other factors can give patients a better insight into the diagnosis and thus a more appropriate treatment plan. These evaluations are categorized as Advanced Semen Analysis.

In the Joshi's Andrology & Urology Centre laboratory, it is possible to perform an advanced Semen analysis.

Advanced semen analysis: DNA fragmentation index test for sperm.

The presence of fragmented DNA in the nucleus of sperm cells has a negative impact on reproductive results. The sperm DNA fragmentation test measures the stability of the chromatin and estimate the percentage of sperm cells that have fragmented DNA.

Any couple doing an assisted reproductive treatment can take the DNA fragmentation test for sperm. This test is especially recommended for men over 35 years of age, history of recurrent miscarriages, history of failed IVF and IUI, history of exposure to gonadotoxins, who have a genitourinary infection or who have received cancer treatment etc..

The DNA fragmentation test can be useful for couples who have had multiple miscarriages, unsuccessfully completed multiple cycles, or who cannot find a reason for their infertility.

·         Advanced semen analysis: Apoptosis -Annexin V test

Apoptosis or cell death plays an important role in spermatogenesis by eliminating sperm cells with structural or functional defects. The presence of an abnormally high level of dead sperm in the ejaculate can adversely affect male fertility.

The Apoptosis -Annexin V test determines the number of damaged sperm cells in the ejaculate and / or the sperm samples reserved for assisted reproduction. The assay uses the Annexin V protein to mark the damaged cells, which are then counted. The quality of samples with abnormally high apoptosis can be improved by specifically removing damaged sperm cells, using the Annexin V MACS Technique.

·         Advanced semen analysis: Oxidative Stress test (ROS)

The sperm cells produce small amounts of reactive oxygen species (ROS, short for reactive oxygen species) that are essential for their normal functioning. This amount of ROS is controlled by the antioxidants present in the fluid from the prostate and seminal vesicles.

However, as the balance between reactive oxygen component production and antioxidant activity shifts, ROS levels will increase. This causes oxidative stress, which damages the sperm and decreases fertility. Increasing the levels of ROS can be reduced through lifestyle changes and a diet rich in antioxidants.

 

·         Advanced Sperm Analysis: Y Chromosome Microdeletion Test

The microdeletions in the AZF factor of the Y chromosome are responsible for about 10-15% of azoospermia and 5-10% of oligospermia cases in men. The Y chromosome microdeletion test examines parts of the Y chromosome by PCR: AZFa, AZFb, AZFc. This identifies possible causes of male infertility.

 

 

Joshi's Andrology & Urology Centre

Address: Neelamma Complex, Opposite Unlimited mall, No 44/2 1st floor, 60 Feet Rd, G Block, Sahakar Nagar, Bengaluru, Karnataka 560092

Appointments: https://joshiuroandrology.com/Pages/Contact-Us, 

Phone: 080 4207 0577

Kidney stones | Kidney stone treatment in Bangalore

Kidney stones | Kidney stone treatment in Bangalore arise because crystals are formed in the urine. Not all kidney stones are painful. But when stones enter the ureter (kidney pipe) and make the flow of urine more difficult, they often cause severe pain called as a renal colic. Most of the patients we see report to the emergency department with severe pain, with or without nausea and vomiting.

Kidney stones  | Kidney stone treatment in Bangalore

Pain relief is the first step in treatment, often combined with medication that can relax the muscles of the ureter. Fluid intake is limited to limit the pressure on the drainage system. Further examinations are then planned, on the one hand to determine the location and size of the stone, and on the other hand to rule out complications.

On the basis of the results of these examinations and in consultation with the patient, the urologist will decide what the Best Kidney stone treatment in Bangalore could be.

Pain relief and waiting for the spontaneous expulsion of the stone: Especially for small stones that are already at the end of the ureter, often the best option

Preparation for the ultimate stone treatment or approach for complicated stones:

Some stones cannot be treated in 1 time due to their location, size or complications (infection, blockage in patients with only 1 kidney, ...). In these patients, a smooth passage of urine must first be guaranteed before the actual treatment of the stone can be started.

Ureteric stent: A Ureteric stent aka DJ stent is a hollow plastic tube with curls on both ends that helps to hold the stent in place. The stent is placed under anesthesia or sedation in the operating room. It passes through the ureter next to the stone and serves to drain “dirty” urine and relieve pressure on the kidney.

Nephrostomy: If placement of a DJ stent is not recommended or is not possible, a nephrostomy must be inserted. This is a drain that is done through a small incision in the back and into the kidney. This procedure can be done under local anesthetic at the radiology department.

Surgical treatment: For the definitive treatment of the stone, the urologist has 3 treatment options available:

ESWL = extracorporeal shockwave lithotripsy

URS (Therapeutic ureterorenoscopy)

PCNL = percutaneous nephrolitholapaxia

ESWL or kidney stone pulverizer

Sound waves are aimed at a focal point. Via X Ray imaging or Ultrasound imaging, the stone is searched and placed in the focus of the shock waves. The purpose of this is to break the stone, so that the pieces of stone can be discharged spontaneously.

 

Not all stones are equally hard, so that not all stones can be treated in this way. Large, hard stones require more energy, so that sometimes several treatment sessions are necessary. Stones in the ureter often break less well, regardless of size and hardness.

Usually 3000 shock waves / session are administered. These are rather painful and in order to focus properly, the patient must remain very still. That is why the procedure is performed under sedation or anesthesia. The patient enters the day hospital on an empty stomach for this purpose.

Although this procedure does not involve any cut on the skin, the shock waves can in exceptional circumstances give rise to bruising. It is therefore very important that the patient reports the use of blood thinners in advance.

Blood in the urine can occur after this procedure.

The fragment of the stone that settles after the procedure can give rise to a new renal colic. Measures here are similar to those for small stone treatment: pain relief as prescribed by the doctor and fluidrestriction. In case of fever or unbearable pain, the emergency department should be contacted immediately.

Ureterorenoscopy (URS)

During this procedure, the urologist uses a small camera through which a working channel runs through the urethra and the bladder to the ureter to search for the stone. Small stones can be caught and removed with a pair of forceps or a basket. Larger stones are fragmented with the laser into fine particles, which can spontaneously wash out. 

The procedure is always performed under general or regional anesthesia in a day hospital or with 1 overnight stay in hospital.

After surgery, many patients might have blood in their urine. Pain (colic pain) can also persist for several days due to swelling of the ureter. Pain relief is prescribed for this.

If the stone or procedure causes damage to the ureter wall, the urologist will leave a DJ stent until the ureter has healed. The stent gives the feeling of frequent and urgent urination. It often also causes blood in the urine (up to a few days after stent removal). The stent is removed after a week in the OPD.

In case of fever or pain that is not controlled with classic pain relief, you must report urgently, regardless of whether a stent was left or not.

Percutaneous Nephrolithotomy (PCNL)

This procedure is used less frequently than ESWL or URS. It is a technique to remove very large stones (> 2cm) from the kidney or the most upper part of the ureter.

During the procedure, a catheter with a balloon is first introduced through the urethra and the bladder into the ureter. Afterwards, the patient is turned on the stomach or on the side. The kidney is punctured through an incision in the back or in the flank, guided by the ultrasound. The resulting channel is stretched and a tube is pushed through which a camera with working channel is inserted into the kidney. Here the stone is usually broken into pieces with the laser or conventional lithotripter, which are then removed from the kidney with forceps. At the end of the procedure, a drain or catheter is inserted into the canal so that the bloody urine can drain properly. The blood remains in the urine for several days.

The procedure is always performed under general anesthesia and the patient is admitted to hospital for 3 to 4 days.

After the procedure, the patient is not allowed to do strenuous exercise or exercise for 3 weeks.

In case of pain, excessive blood flow or fever, the patient should immediately go to the emergency department

For more information about kidney stones, please consult Dr. Praveen B Joshi.

Urological center | URINARY TRACT INFECTION TREATMENT IN BANGALORE

 

Welcome to the Urological Center of reconstructive urinary treatment in Bangalore. You can contact us for all urological care and treatment. We help you as quickly and as well as possible, with innovative equipment and the latest techniques, at a high scientific level.

Urinary tract

The urinary tract performs an important task for the health of our body: they filter the blood and ensure the excretion of waste products and toxic substances. The urinary system or urinary tract consists of several organs: kidney, adrenal gland, ureter, bladder and urethra. In those organs, just like in other places in our body, complaints or problems can arise.

Diseases

Kidneys:

Kidney cyst

A kidney cyst is a bubble filled with fluid, typically located on the outer edge of the kidney. It's a benign condition.

Kidney stone

A kidney stone is deposition of salts and crystal formation that forms in one of the kidneys. In the first instance, this stone is located in the kidney: you usually cannot feel such a kidney stone.

Ureter

Ureter stone

A painful renal colic occurs when the kidney stone 'breaks off' and falls from the kidney into the ureter (ureter = ureter), blocking the normal passage of urine. A ureteric stone is therefore a kidney stone that moves out of kidney at some point and then gets stuck in the ureter.

Bladder

Bladder infection

A bladder infection is most common form of UTI across all age groups. Most people experience burning urination and increased frequency and urgency sometimes associated with fever.

Bladder pain syndrome

When the bladder pain syndrome causes a defect at the level of the bladder causing chronic irritation with reduced capacity of the urinary bladder. Bladder pain syndrome is associated with lower abdominal pain and 'small bladder' symptoms like urgency and frequency.

Bladder stone

A bladder stone usually forms when the urine from the bladder can’t get emptied freely. A bladder stone that remains in place can grow in the bladder and make urination difficult.

Loss of urine

Incontinence is the same as involuntary loss of urine.

You can contact joshi's andrology & urology centre for the diagnosis and treatmentof disorders of the urinary and reproductive health. Here you will find practical information about urological symptoms disorders and the different treatment methods.

 

Make an appointment: https://joshiuroandrology.com/Pages/Contact-Us

Address: 

Joshi's Andrology & Urology Centre

Neelamma Complex, Opposite Unlimited mall,

No 44/2, 1st floor, 60 feet road,

Sahakara Nagar, G Block, Sahakara Nagar,

Bengaluru, Karnataka 560092

Contact Number:

Phone-Number : 080 - 42070577

Mobile-Number : +91-8197371247